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2 edition of Sulpiride and other benzamides found in the catalog.

Sulpiride and other benzamides

International Workshop on Sulpiride and other Benzamides (1978 Florence)

Sulpiride and other benzamides

experimental and clinical pharmacology

by International Workshop on Sulpiride and other Benzamides (1978 Florence)

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  • 1 Currently reading

Published by Italian Brain Research Foundation Press, Distributed outside Italy by Raven Press in Milan, New York .
Written in English


Edition Notes

Statementeditors Pier Franco Spano... [et al.].
SeriesMonograph series
ContributionsSpano, Pier Franco.
ID Numbers
Open LibraryOL14094662M

Sulpiride (sold as Meresa®, Sulpirid Ratiopharm®, Sulpirid Neuraxpharm®, Bosnyl, Dogmatil®) is an anti-psychotic drug used mainly in the treatment of psychosis (e.g. schizophrenia) and is a substituted benzamide. Sulpiride is more commonly used in Europe and Japan. So far it has not been approved in the US and number ATC code #N#N05AL DrugCentral is online drug information resource created and maintained by Division of Translational Informatics at University of New Mexico.

Sulpiride, sold under the brand name Dogmatil among others, is an atypical antipsychotic (although some texts have referred to it as a typical antipsychotic) medication of the benzamide class which is used mainly in the treatment of psychosis associated with schizophrenia and major depressive disorder, and sometimes used in low dosage to treat anxiety and mild status: UK: POM (Prescription only), In general: ℞ . Request PDF | Sulpiride for schizophrenia | The antipsychotic drug sulpiride was formulated over 20 years ago and was marked as having a low incidence of adverse effects and an effect on the.

Fontaine J, Reuse J. Pharmacological analysis of the effects of substituted benzamides on the isolated guinea-pig ileum. Study of metoclopramide, sulpiride, bromopride, tiapride and sultopride. Arch Int Pharmacodyn Ther. Sep; (1)– Giger M. Toxische Wirkungen von Metoclopramid. Schweiz Rundsch Med Prax. Jul 22; 64 (29) Cited by: 5. Sulpiride is a selective antagonist at dopamine D 2, D 3 and 5-HT 1A receptors. Antagonism at 5-HT 1A dominates in doses exceeding mg daily. In doses of to 1, mg sulpiride shows mild sedating and antipsychotic activity. Its antipsychotic potency compared to chlorpromazine is only (1/5). In low doses (in particular 50 to mg daily) its prominent feature is antagonism of.


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Sulpiride and other benzamides by International Workshop on Sulpiride and other Benzamides (1978 Florence) Download PDF EPUB FB2

Get this from a library. Sulpiride and other benzamides: experimental and clinical pharmacology. [Pier Franco Spano; Italian Brain Research Foundation.;]. sulpiride and other benzamides as a tool for the study of a class of dopamine receptors Sulpiride is a substituted, benzamide, and similar to metoclopramide it possesses a pronounced antiemetic activity (Justin-Besancon et al., ).Cited by: 1.

The book contains papers on the interaction of sulpiride and other substituted benzamides with dopamine receptors where the result of receptor stimulation Book Edition: 1. Sulpiride is a typical antipsychotic based on antagonism of postsynaptic D 2 dopamine receptors. Agonism at the gamma-hydroxybutyrate receptor may contribute to its antipsychotic properties.

Sulpiride has fewer extrapyramidal side effects, but also reduced antipsychotic potency, as compared with many other typical lower doses than used for antipsychotic treatment, its. Sulpiride and Other Benzamides as Specific Antagonists at the D2 Dopamine Receptors.

By Spano PF, Carboni E, Garau L, Memo M, Govoni S and Trabucchi M. Publisher: Pergamon Press. Year: OAI identifier: oai: In adults, other dopamine receptor antagonists such as risperidone, pimozide, and sulpiride seem to be more effective than tiapride.

Today it is unknown whether new atypical neuroleptic drugs including the benzamide amisulpride are more effective than the older benzamides tiapride and by: 7. Sulpiride, a substituted benzamide is classified as low potent AA.

It is a weak but highly selective antagonist of DA-D2 receptors (Müller-Vahl, ). Sulpiride has been assumed to be the most commonly prescribed benzamide for the treatment of tics in Europe (Eddy et al., ). Sulpiride: Sulpiride is indicated for the treatment of schizophrenia. Remoxipride: Remoxipride is an atypical antipsychotic once used for the treatment of schizophrenia.

Amisulpride: Investigated for use/treatment in schizophrenia and schizoaffective disorders, mania. Both sulpiride and arsenic trioxide prolong the QT interval.

Most manufacturers advise avoiding the use of two or more drugs that are associated with QT prolongation. Increasing age, female sex, cardiac disease, and some metabolic disturbances (notably hypokalaemia) predispose to QT prolongation. Amisulpride and sulpiride, like many medicines, do not work straight away.

For example, it may take several days or even weeks for some symptoms to improve. To begin with, some people find that amisulpride or sulpiride may help them feel more alert and less sedated. Later, (usually in two or three weeks) other symptoms should begin to Size: KB.

Sulpiride and other benzamides' displacement of [3H]-spiroperidol binding to rat and dog anterior pituitary dopaminergic receptors was found to be selectively sodium dependent, while typical.

Sulpiride is a member of the group of substituted benzamides, which are structurally distinct from the phenothiazines, butyrophenones and thioxanthenes. Current evidence suggests that the actions of sulpiride hint at an important distinction between different types of dopamine receptors or receptor mechanisms in the brain.

However, the inhibitory potency of various antipsychotic drugs does not fully correlate with their behavioral and clinical efficacy (33), Moreover, we found that sulpiride and other substituted benzamides, which behave as strong DA antagonists in various animal tests and in clinical applications, fail to inhibit, in contrast to classical Cited by: 2.

Author(s): Spano,Pier Franco; International Workshop on Sulpiride and Other Benzamides,( Florence); Italian Brain Research Foundation.

Title(s): Sulpiride and other benzamides: experimental and clinical pharmacology/ editors, Pier Franco Spano. Amisulpride, a benzamide, chemically related to sulpiride and sultopride is used since It is efficacious for the treatment of schizophrenia (Mauri et al., ).

1 However, successful treatment of TS with amisulpride has only been published in case reports (Fountoulakis et al., ; Trillet, Moreau, Daléry, de Villard, & Aimard, ). The dopaminergic antidepressant action of substituted benzamides such as sulpiride, has been proposed, since the late s, by several authors and extensively explored in Cited by: The book contains papers on the interaction of sulpiride and other substituted benzamides with dopamine receptors where the result of receptor stimulation is not a.

Contents of the pack and other information What Sulpiride Tablet contains The active ingredient is sulpiride. The other ingredients are lactose monohydrate, microcrystalline cellulose, povidone K30, sodium starch glycollate and magnesium stearate.

(see Section 2 'Important information about some of the other ingredients of Sulpiride Tablets}. Bressolle F, Bres J, Brun S, Rechencq E. Assays are proposed for sulpiride and other benzamides, vincamine and naftazone in plasma (or blood) and urine with direct UV reflectance spectrophotometry on this are applied directly on TLC along with a calibration curve on each by: 2.

Sulpiride (SPD) 5-(aminosulfonyl)-N-[(1-ethylpyrrolidinyl)methyl]methoxybenzamide, a substituted benzamide with antipsychotic properties, acts as antagonist of the dopamine D 2 receptors, a property which distinguishes from other antipsychotic particular feature may explain the very low incidence of side effects on the extrapyramidal by: 8.

Sulpiride (SPD) 5-(aminosulfonyl)-N-[(1-ethylpyrrolidinyl)methyl]methoxybenzamide, a substituted benzamide with antipsychotic properties, acts as antagonist of the dopamine D 2 receptors, a property which distinguishes from other antipsychotic agents.

This particular feature may explain the very low incidence of side effects on the Cited by: 8.for sulpiride Monitoring of patient parameters Sulpiride does not affect blood pressure to the same extent as other antipsychotic drugs and so blood pressure monitoring is not mandatory for this drug.Other investigators suggest that increasing the dose of progestogen alone would achieve the same effect as combined sulpiride therapy.

Duodenal Ulcer: Oral sulpiride 50 to mg 3 times daily was reported to enhance the efficacy of antacids (aluminum-magnesium hydroxide) on duodenal ulcer healing in a .